telomere

Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.

結(jié)論端?？s短并激活端粒酶是涎腺腫瘤形成的重要因素.

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Telomerase system is the genetic name of telomerase and telomere.

端粒酶系統(tǒng)是端粒和端粒酶的總稱(chēng).

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Telomere locates on the terminal of DNA containing repeat DNA sequence.

端粒是位于染色體末端的串聯(lián)重復(fù)核苷酸序列.

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ALT and TA mechanisms are dominant maintenance mechanisms of the telomere length.

端粒長(zhǎng)度的維持機(jī)制主要有ALT機(jī)制和TA機(jī)制.

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Considering the risks of telomere - extension therapy, he thinks that scientists have bigger fish to fry.

因?yàn)檠娱L(zhǎng)端粒療法具有危險(xiǎn), 他認(rèn)為還有更大的問(wèn)題需要科學(xué)家去解決.

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We summarize the present research of telomerase and telomere and their applications on ocular disease.

在此,我們就端粒、端粒酶研究現(xiàn)狀及其與眼科疾病的關(guān)系和應(yīng)用進(jìn)展作一綜述.

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Objective To evaluate the role of telomere and DCC in tumor transformation and progression.

目的　分析端粒長(zhǎng)度及DCC基因 mRNA 表達(dá)在大腸癌及腺瘤發(fā)生發(fā)展中的作用.

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The telomere is like a cellular clock, because every time a cell divides, the telomere shortens.

端粒就像是細(xì)胞的時(shí)鐘, 因?yàn)樵诿看渭?xì)胞分裂時(shí)它都首先要縮短.

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Therefore, TRF 2 may protect chromosome ends by maintaining the correct structure at telomere termini.

因此, TRF2可保護(hù)染色體末端保持正確的結(jié)構(gòu),端粒末端.

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Can telomere maintenance be eliminated effectively ( and selectively ) enough by more tractable approaches?

端粒維持可以由足夠有效地 ( 或選擇性地 ) 更易控制的途徑而有效地被排除 嗎 ?

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Researchers estimate that telomere maintenance activity occurs in about 90 % of human cancers.

研究人員估計(jì),90%的癌癥中端粒一直處于活躍狀態(tài).

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Overall, the study participants had an average telomere loss of 21 nucleotides ( structural units ) per year.

總的來(lái)說(shuō), 該項(xiàng)研究的參與者每年平均損失21個(gè)核甘酸 ( 結(jié)構(gòu)單位 ).

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Telomere is at the end of the chromosome in eukaryotic cells and protects chromosomes.

摘要端粒位于真核細(xì)胞染色體末端,起保護(hù)染色體末端的作用.

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