Cyclin - cdk compound is composed of Cyclin and cdk different cell cycle.
多種腫瘤存在著Cyclin的異常表達(dá),cdk的激活及其抑制因子的丟失.
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CDK activation by cyclin binding.
1)CDKs結(jié)合cyclin后活化.
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Rapamycin arrested cell cycle in G 1 phase to antitumor by degrading the CDK - cyclin complexes kinase activity.
Rapamycin還能通過降低CDK-cyclin復(fù)合物激酶的活性,使細(xì)胞周期阻滯在G1期,從而發(fā)揮抗腫瘤的作用.
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Cell cycle is mainly regulated by cyclin, cyclin dependent kinase ( CDK ) and cyclin dependentkinase inhibitor ( CDKI ).
細(xì)胞周期主要是由細(xì)胞周期蛋白 ( cyclin), 細(xì)胞周期蛋白依賴性激酶 ( CDKs ) 和CDK抑制蛋白(CDKI ) 來調(diào)控的.
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Objective To construct recombinant expressing Cyclin D 1 and CDK 4 proteins.
[目的]建表達(dá)人細(xì)胞周期蛋白D1及細(xì)胞周期蛋白激酶CDK4融合蛋白的重組體.
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Cell cycle in plants is controlled byactivity of cyclin - dependent kinase ( CDK ) complexes.
植物細(xì)胞周期主要由細(xì)胞周期蛋白依賴性激酶 ( CDK ) 復(fù)合物調(diào)控.
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Cyclin D 1 and CDK 4 proteins were expressed correctly in insect cells and had their biological activity.
成功構(gòu)建了細(xì)胞周期蛋白D1及CDK4真核桿狀病毒表達(dá)載體,并且在昆蟲細(xì)胞中正確表達(dá)了具有生物活性的細(xì)胞周期蛋白D1及CDK4融合蛋白.
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Protein serine theronine phosphatase inhibitor or cyclin dependent kinase ( CDK ) inhibitors could abolish the enhancement.
而蛋白絲氨酸蘇氨酸磷酸酯酶抑制劑以及細(xì)胞周期蛋白依賴性激酶 ( dk ) 制劑可阻斷該凋亡敏感性增強(qiáng)效應(yīng).
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CDK and cyclin are key molecules that control and coordinate DNA - synthesis, chromosome separation and cell division.
CDK和細(xì)胞周期蛋白是控制和協(xié)調(diào)DNA合成 、 染色體分離和細(xì)胞分裂的重要分子.
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Effects on the protein expression of cyclin A , B _ 1 and D _ 1 were assessed by Western Blot.
Western印跡檢測(cè)細(xì)胞周期蛋白D1 、 A和B1表達(dá)的變化.
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The expression of cyclin D 1 and CDK 4 were detected by RT PCR method.
RTPCR檢測(cè)細(xì)胞周期素D1(cyclinD1)、細(xì)胞周期蛋白依賴激酶4(CDK4)mRNA的表達(dá).
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Conclusions : Overexpression of cyclin D 1 and CDK 4 may involve in the onco - pathogenesis of ESC.
我們?cè)谙鄳?yīng)的癌旁組織中亦發(fā)現(xiàn)cyclinD1和CDK4的過表達(dá).
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Objective: To investigate the expressions of cyclin E, CDK 2, and Ki - 67 and their clinical significance in leukemia.
的: 探討白血病細(xì)胞周期素E(cyclinE) 、 細(xì)胞周期蛋白依賴性激酶2(CDK2)、細(xì)胞增殖相關(guān)抗原(Ki67)在白血病中的表達(dá)及其臨床意義.
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