The majority of AMPA receptor is a GluR 2 - containing heterotetramer in hippocampus.
在海馬中大部分AMPA受體是以含 GluR2 的異四聚體的形式存在.
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When AMPA receptor is activated, lots of intracellular Ca ~ ( 2 + ) result in neurons injury.
在AMPA受體激活時, 大量 Ca2 +內(nèi)流導致神經(jīng)損傷.
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GluR 2 - lacking AMPA receptors appeared high permeability to Ca 2 +.
缺乏GluR2的AMPA受體通道對Ca2+有很高的通透性.
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Objective To explore the epileptogenesis effect of the AMPA receptors.
目的 為了研究AMPA受體在癲癇發(fā)生中的作用.
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These attach themselves to nerve - cell proteins called AMPA receptors.
這些依附于神經(jīng)元細胞自己的叫做AMPA接收器.
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AMPA receptor has the important role in epilepsy about its pathogenesis study and therapy.
AMPA受體 對于癲癇發(fā)病機制的研究和治療均有重要作用.
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At these synapses , most of baseline synaptic transmission is mediated by glutamate AMPA receptors.
在正常條件下, 大多數(shù)的突觸反應是由谷氨酸的AMPA受體傳遞的.
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AMPA receptors mediate the fast excitatory synaptic transmission in the central nervous system.
AMPA受體介導了中樞神經(jīng)系統(tǒng)絕大部分快速型的興奮性突觸傳遞.
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Objective To investigate the role of changes in AMPA receptor GluR 2 subunit expression in epileptogenesis.
目的研究在癲癇發(fā)病過程中,谷氨酸對AMPA受體GluR2亞單位表達變化的影響.
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The suitable concentration of AMPA is 2.3μ M, which leaded to the Ratio of 0.8±0.14.
AMPA作用的最適濃度為2.3μM, 反映細胞內(nèi)[Ca2+]高低的指標—Ratio值約為0.80±0.14.
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The nature AMPA receptor is normally Ca ~ ( 2 + ) impermeable due to the expression of GluR 2 subunit.
由于GluR2亞單位的表達天然AMPA受體通道對 Ca2 +不通透.
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